Heavy-Chain Isotype (Class) Switching.ДЄNTIBODY RESPONSES TO T-INDEPENDENT ANTIGENS. Presentation of Antigens by B Lymphocytes to Helper T Cells.Д®xtrafollicular and Germinal Center Reactions. Role of Innate Immune Signals in B Cell Activation.ДЇunctional Consequences of B Cell Activation by Antigen.ДЄctivation and Migration of Helper T Cells and B cells. PHASES AND TYPES OF HUMORAL IMMUNE RESPONSES. RESISTANCE OF PATHOGENIC MICROBES TO CELL-MEDIATED IMMUNITY. Subsets of CD4+ Helper T Cells Distinguished by Cytokine Profiles.ДIFFERENTIATION AND FUNCTIONS OF CD8+ CYTOTOXIC T LYMPHOCYTES. TYPES OF T CELLвЂ“MEDIATED IMMUNE REACTIONS. MIGRATION OF T LYMPHOCYTES IN CELL-MEDIATED IMMUNE REACTIONS.ДECLINE OF THE IMMUNE RESPONSE.

Secretion of Cytokines and Expression of Cytokine Receptors.Дifferentiation of Naive T Cells into Effector Cells. Stimuli for Activation of CD8+ T Cells.Д«IOCHEMICAL PATHWAYS OF T CELL ACTIVATION.

Role of Costimulation in T Cell Activation. Role of Adhesion Molecules in T Cell Responses. Maturation and Selection of T Lymphocytes.Д®arly Steps in T Cell Maturation.ДҐ - T CellвЂ“Mediated Immunity: Activation of T Lymphocytes. Role of the Pre-BCR Complex in B Cell Maturation. Mechanisms of V(D)J Recombination.Д®arly Steps in B Cell Maturation. Somatic Recombination and Expression of Antigen Receptor Genes. Physiologic Significance of MHC-Associated Antigen Presentation.ДЄNTIGEN RECOGNITION BY B CELLS AND OTHER LYMPHOCYTES.Д¤ - Antigen Recognition in the Adaptive Immune System: Structure of Lymphocyte Antigen Receptors and Development of Immune Repertoires.ДЄNTIGEN RECEPTORS OF LYMPHOCYTES.ДЄntigen Recognition by the T Cell Receptor.ДEVELOPMENT OF B AND T LYMPHOCYTES. Internalization and Proteolysis of Antigens.Д«inding of Peptides to Class II MHC Molecules.Д¬ross-Presentation of Internalized Antigens to CD8+ T Cells. Transport of Peptide-MHC Complexes to the Cell Surface. PROCESSING AND PRESENTATION OF PROTEIN ANTIGENS.

Inheritance Patterns and Nomenclature of HLA Genes. STRUCTURE AND FUNCTION OF MAJOR HISTOCOMPATIBILITY COMPLEX MOLECULES. ROLE OF INNATE IMMUNITY IN STIMULATING ADAPTIVE IMMUNE RESPONSES.ДЈ - Antigen Capture and Presentation to Lymphocytes: What Lymphocytes See.ДЄNTIGENS RECOGNIZED BY T LYMPHOCYTES.Д¬APTURE OF PROTEIN ANTIGENS BY ANTIGEN-PRESENTING CELLS. Phagocytosis and Destruction of Microbes. Recruitment of Phagocytes to Sites of Infection and Tissue Damage. Other Plasma Proteins of Innate Immunity. Phagocytes: Neutrophils and Monocytes/Macrophages. GENERAL FEATURES AND SPECIFICITY OF INNATE IMMUNE RESPONSES.Д¬ytosolic RNA and DNA Sensors. Lymphocyte Recirculation and Migration into Tissues.Дў - Innate Immunity: The Early Defense Against Infections. Peripheral (Secondary) Lymphoid Organs and Tissues. This focused, easy-to-understand volume uses full-color illustrations and clinical images, useful tables, and practical features such as Summary Point boxes, end-of-chapter review questions, glossary terms, and clinical cases-all designed to help students master this complex topic in the most efficient, effective manner possible. Meticulously reviewed and updated for todayвЂ™s medical students, Basic Immunology, 6th Edition, is a concise text expertly written by the same distinguished author team as the best-selling, comprehensive text, Cellular and Molecular Immunology.

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